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Gerard W O'Keeffe Selected Research

Growth Differentiation Factor 5

1/2022Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease.
1/2021Growth differentiation factor 5 exerts neuroprotection in an α-synuclein rat model of Parkinson's disease.
10/2012Transplantation of novel human GDF5-expressing CHO cells is neuroprotective in models of Parkinson's disease.
9/2005The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson's disease treatment.

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Gerard W O'Keeffe Research Topics

Disease

32Parkinson Disease (Parkinson's Disease)
05/2022 - 09/2004
8Neurodegenerative Diseases (Neurodegenerative Disease)
05/2022 - 03/2012
4Neuroblastoma
04/2020 - 07/2017
3Disease Progression
01/2022 - 03/2018
3Autism Spectrum Disorder
01/2022 - 01/2018
2Inflammation (Inflammations)
06/2021 - 01/2018
2Neoplasms (Cancer)
01/2019 - 07/2017
2Pre-Eclampsia (Preeclampsia)
07/2018 - 02/2015
1Mitochondrial Diseases (Mitochondrial Disease)
05/2022
1COVID-19
01/2022
1Autistic Disorder (Autism)
11/2021
1Dyskinesias (Dyskinesia)
11/2021
1Neurodevelopmental Disorders
06/2021
1Brain Injuries (Brain Injury)
10/2020
1Epilepsy (Aura)
01/2019
1Congenital Disorders of Glycosylation
01/2019
1Lissencephaly
01/2019
1Intellectual Disability (Idiocy)
01/2019
1Birth Weight (Birth Weights)
10/2018
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2018
1Cognitive Dysfunction
04/2017
1Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain)
08/2015
1Chronic Pain
02/2013
1Hyperalgesia
02/2013
1Hereditary Sensory and Autonomic Neuropathies (HSAN)
02/2013
1Pain (Aches)
02/2013
1Wounds and Injuries (Trauma)
03/2012

Drug/Important Bio-Agent (IBA)

14SynucleinsIBA
05/2022 - 11/2016
11Nerve Growth Factors (Neurotrophins)IBA
01/2022 - 09/2004
5Oxidopamine (6 Hydroxydopamine)IBA
01/2022 - 01/2014
4Growth Differentiation Factor 5IBA
01/2022 - 09/2005
4CytokinesIBA
11/2021 - 02/2015
3NeurotoxinsIBA
01/2022 - 01/2019
3MicroRNAs (MicroRNA)IBA
10/2020 - 08/2015
3Cytotoxins (Cytolysins)IBA
01/2019 - 07/2017
2MC1568IBA
01/2022 - 01/2019
2Histone Deacetylase InhibitorsIBA
01/2022 - 07/2017
2Bone Morphogenetic Protein ReceptorsIBA
08/2020 - 04/2020
2Histone Deacetylases (Histone Deacetylase)IBA
06/2020 - 07/2017
2Messenger RNA (mRNA)IBA
10/2018 - 12/2016
2Biomarkers (Surrogate Marker)IBA
03/2018 - 02/2015
2Histones (Histone)IBA
07/2017 - 10/2016
2Neuroprotective AgentsIBA
05/2017 - 02/2014
1Interleukin-17 (Interleukin 17)IBA
01/2022
1Interleukin-4 (Interleukin 4)IBA
11/2021
1Levodopa (L Dopa)FDA LinkGeneric
11/2021
1NociceptinIBA
11/2021
1Opioid Analgesics (Opioids)IBA
11/2021
1GTP-Binding Proteins (G-Protein)IBA
11/2021
1Opioid Receptors (Opioid Receptor)IBA
11/2021
1at-403IBA
11/2021
1Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
08/2020
1Bone Morphogenetic Protein 2IBA
08/2020
1NeurturinIBA
08/2020
1Indicators and Reagents (Reagents)IBA
01/2019
14-hydroxychalconeIBA
01/2019
1FlavonoidsIBA
01/2019
1EpitopesIBA
01/2019
1Polysaccharides (Glycans)IBA
01/2019
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2019
1Cisplatin (Platino)FDA LinkGeneric
01/2019
1isoliquiritigenin (GU 17)IBA
01/2019
1CorticosteroneIBA
01/2018
1ORALIT (ORS)IBA
01/2018
1CaspasesIBA
07/2017
1Reactive Oxygen Species (Oxygen Radicals)IBA
07/2017
1romidepsin (FK228)FDA Link
07/2017
1AS 35IBA
07/2017
1Pharmaceutical PreparationsIBA
07/2017
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
04/2017
1Histone Acetyltransferases (Histone Acetyltransferase)IBA
10/2016
1Activins (Activin)IBA
02/2015
1activin AIBA
02/2015
1Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
01/2015
1Proteins (Proteins, Gene)FDA Link
10/2014
1Nerve Growth Factor (NGF)IBA
02/2013
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
02/2013

Therapy/Procedure

12Therapeutics
01/2022 - 02/2013
3Cell Transplantation
10/2014 - 03/2012
2Drug Therapy (Chemotherapy)
07/2021 - 07/2017
1Pain Management
02/2013
1Transplantation
10/2012